报告题目：Single-cell and spatial analyses of the human reproductive system

报告人：Prof. Jun Li

密歇根大学医学院人类遗传学教授，计算医学与生物信息学教授兼副主任。毕业于北京大学物理专业，并于加州理工大学获得生物物理/电生理博士学位，后于斯坦福大学从事遗传学/基因组学博后研究工作。加入密歇根大学后参与密歇根医学院的领导研究计划，并被选为 AAAS 研究员和 AIMBE 研究员。

scRNA-seq methods have transformed our ability to measure cellular heterogeneity in complex tissues. The next frontier lies in spatial analysis, adopting imaging approaches that are high-resolution (e.g., visualizing single RNA molecules) and highly multiplexed (for hundreds of genes at a time) to survey the spatial organization of molecules and cells in large tissue sections. Our group has applied the MERFISH technology and scRNA-seq to study mammalian spermatogenesis, and contributed to the Human Cell Atlas by creating female reproductive tissue atlases for the fallopian tube, ovary, and uterus. This enhanced understanding of cellular functions in healthy tissues has accelerated translational research, addressing long-standing questions in reproductive aging, infertility, and related cancers. Meanwhile the field faces increasingly pressing challenges in integration across diverse technologies, computational tools, and ontologies.

时间:2024年8月23日(周五)9:00~10:30

地点:生殖医学中心五层会议室

主持人:袁鹏 副研究员

会议内容:学术报告半小时、学术交流1小时